G.H. Nasery; M. Mazandarani; M.B. Rezaee
Volume 24, Issue 2 , August 2008, , Pages 126-134
Abstract
Tanacetum parthenium L. is one of the most important medicinal herbs that grows wild and wide distribution near the river, road and sunny positions in forest and mountainous rangelands in South East of Golestan Province, especially in 800-1250m above the sea level in medium soil texture, neutral PH and ...
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Tanacetum parthenium L. is one of the most important medicinal herbs that grows wild and wide distribution near the river, road and sunny positions in forest and mountainous rangelands in South East of Golestan Province, especially in 800-1250m above the sea level in medium soil texture, neutral PH and organic carbon percent with medium to high. In addition to its ecological and ethnopharmacological needs essential oil composition of this plant were also studied. Artemisia annua, Artemisia absintium, Mentha longifolia, Mentha aquatica, Thymus carmanicus, Cuminum cyminum,Echium amoenum, andSalix alba for sedative of headache and menstrual pain, cold, fever, inflammation and healing wound. Flowering aerial parts of this plant were collected in July 2006 in 1100m of Ziarat mountainous region, 6km far from Gorgan city in Golestan province. The essential oil of different parts of plant obtained by water distillation and analyzed by GC/MS. Camphor (53.5%), a-pinene (17.7%) and a-bisabolol oxide B (10.5%) were the major components of flower oil. But in leaf oil, camphor (38.9%), a-pinene (8.4%), germacrene D (6.3%) and g-terpinene (8.2%) were the main components. The results confirm use of this plant by the rural healers for curing many types of the sedative pain and other ailments.
T. Dadgar; E. Ghaemi; M. Asmar; M. Mazandarani; M. Bazueri
Volume 23, Issue 1 , May 2007, , Pages 73-85
Abstract
Staphylococcu aureus is an important cause of community and hospital acquired infections. Infections caused by methicillin resistant S. aureus (MRSA) are mainly nosocomial and are increasing in all around the world. Many attempts have been made by the researchers to find new compounds as ...
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Staphylococcu aureus is an important cause of community and hospital acquired infections. Infections caused by methicillin resistant S. aureus (MRSA) are mainly nosocomial and are increasing in all around the world. Many attempts have been made by the researchers to find new compounds as an appropriate substitute for these antibiotics. In this study antimicrobial activities of aqueous and boilling extracts of 6 medicinal plants species collected from Golestan province on clinical and standard strains of MRSA and MSSA were assessed by disc diffusion method. Each test was repeated 3 times and mean inhibition zone was recorded. The boilling and aqueous extracts of 5 and 3 plants showed the best anti staphylococcal effect, respectively. The boilling extract of Artemisia sieberi, Punica granatum, which the maximum inhibition zone was 16.6 mm. raised the most outstanding in vitro antibacterial activities. As a result boilling extracts had better antibacterial effects than aqueous extract.
E. Ghaemi; D. Khorshidi; A. Moradi; A. Seifi; M. Mazendrani; M. Bazouri
Volume 22, Issue 3 , November 2006, , Pages 242-249
Abstract
Daily increasing of Staphylococcus aureus resistance to various antibiotics in particular penicillin and Methecilin has led the scientist to look for new medicines in this area. In an in vitro laboratory studies, it has been demonstrated that ethanolic extract of Lemon verbena can prevent ...
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Daily increasing of Staphylococcus aureus resistance to various antibiotics in particular penicillin and Methecilin has led the scientist to look for new medicines in this area. In an in vitro laboratory studies, it has been demonstrated that ethanolic extract of Lemon verbena can prevent the growth of Staphylococcus aureus. In this study the efficacy of ethanolic extract of Lemon verbena against Staphylococcus aureus skin infection were assessed in an in vivo, in animal model. We inoculated 200λ of Staphylococcus aureus suspension with turbidity equal to 0.5 McFarland, interadermally on the shoulder of 63 laboratory 20-30 gram mice. The mice were divided in to 4 groups, 2 control groups: negative(without treatment) and positive (treated with Mupirocin) and 2 test groups that treated for 7 days by ointment prepared from ethanol extract of Lemon verbena (group3), or injection of Lemon verbena solution (group 4). The status of wounds and the rate of recovery was studied, and the presence of local pus after dissection of mice on day 8 recorded and compared with each other. The wound appearance in the second day, on the injection site of S. aureus, in groups1, 4, 3 and 2 were 84.2%, 66.7%, 46.2% and 23.1%, respectively. In the last day, the lesion still was remained in 78.9, 23.1, 92.3 and 77.7% in group 1 -4, respectively. The necrotic and wide wounds were more observed in groups 1 and 3 versus two other groups. The results from this investigation indicated that the ointment prepared from ethanol extract of Lemon verbena is a proper medication to prevent the skin infection by Staphylococcus aureus in the early phase but injected solution of this extract cannot show this effect, and none of them can prevent the wound itself completely.
